Diabetes and heart disease ppt


Az előadások a következő témára: "Cardiovascularis kockázatcsökkentés a diabetológus szemével"— Előadás másolata: 1 Cardiovascularis kockázatcsökkentés a diabetológus szemével Balatonaliga, május The Verona Diabetes Complications Study showed that, in diabetic and non-diabetic subjects, insulin resistance is associated with several cardiovascular risk factors, including hyperglycaemia, dyslipidaemia and hypertension.

Hypertonia és diabetes krónikus vesebetegségben

The study identified insulin resistance as an independent risk factor for cardiovascular disease. HDL cholesterol concentrations are increased and there is a jardiance tapasztalatok of small dense, atherogenic, LDL particles in patients. PAI-1 plasminogen activator inhibitor-1 : PAI-1 is a major regulator of plasminogen activation and plays an important role in blood clotting.

PAI-1 concentrations are increased in patients with type 2 diabetes. BPH benign prostatic hyperplasia : BPH is a disease that involves the enlargement of the prostate, particularly in elderly men.

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There is a strong association between insulin resistance and BPH. It is now known to exert a variety of catabolic effects which may impair cellular insulin action, increase lipolysis and inhibit glucose transporter 4 GLUT4 expression.

MCP-1 monocyte chemotactic protein-1 : MCP-1 is involved in inflammation by mediating the migration of monocytes and T-cells into inflammatory sites.

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MMP-9 matrix metalloproteinase-9 : Matrix metalloproteinases are a family of membrane-bound zinc-endopeptidases that can degrade all of the components of the extracellular matrix and are implicated in the pathology of atherosclerotic plaque rupture. MMP-9 concentrations are raised in type 2 diabetes and may confer an increased risk of atherosclerotic disease. References 1.

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Bonora E, et al. Diabetes Care ; 2. Drugs ; 58 Suppl 1 Laakso M. Int J Clin Pract Suppl ; Over the follow-up period, subjects experienced and incident cardiovascular event heart attack, stroke, heart surgery, angina, or CVD death.

Cardiovascular Disease Burden in Type 2 Diabetes: Strategies to Improve Outcomes

Reference Hanley AJ et al. Diabetes Care ; 16 Klinikai kórformák Inzulinrezisztencia Hyperinsulinaemia 17 Causes of mortality in diabetic patients Myocardial infarction Diabetes and heart disease ppt are therefore the three main targets for therapeutic intervention.

Hypertonia ©s diabetes kr³nikus vesebetegs©gben

Antihypertensive and lipid-lowering treatments cukorbetegség láb important, but are outside the scope of this presentation. We will concentrate on a review of the evidence demonstrating that the choice of antidiabetic therapy and choice of treatment approach for managing hyperglycaemia have significant influence in reducing morbidity and mortality in type 2 diabetes.

The Lancet UKPDS is the longest and largest prospective randomised controlled trial dedicated to a study of type 2 diabetics ever carried out.

Az előadások a következő témára: "A hagyományos kardiovaszkuláris rizikófaktorok és a diabetes"— Előadás másolata: 1 A hagyományos kardiovaszkuláris rizikófaktorok és a diabetes microvascularis szövődményeinek összefüggése Prof. Kempler Péter egyetemi tanár Semmelweis Egyetem I.

The study, managed from Oxford but conducted in 23 centres around the UK is also a rich source of diabetes and heart disease ppt data on the natural history of diabetes. Lancet HbA1C increased steadily with time in the conventional treatment arm.

The intensive glucose control regimen induced an initial fall in HbA1C over the first year, after which this parameter also increased at a similar rate.

  1. Kiss István.
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  5. They are major risk factors for the developmentand progression of endothelial dysfunction and atherosclerosis,and contribute to the progression of renal failure—yetthese patients tend to be less intensely treated than patientswith normal renal function.

Intensive therapy achieved significantly lower HbA1C values throughout the study, with a median difference of 0. However, intensive treatment based primarily on a monotherapy approach, did not maintain optimal glycaemic control reflecting the progressive nature of type 2 diabetes.

Lancet ;— Intenzív 7. Kardiovaszkuláris és összmortalitás 32 Hyperglykaemia és szövődmények Improving the Prognosis of Patients with Type 2 Diabetes Slide In addition, the risk of microvascular complications increases markedly as HbA1C rises. Management approaches which achieve near normal glycaemic control are likely to have the biggest impact in reducing the incidence of heart attacks.

Diabetes Care Carey DG. Obesity Res ; — Lebovitz H, et al.

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J Clin Endocrinol Metab ; — St John Sutton M, et al. Diabetes Care ; — Cobitz A, et al. DALM Abstract and poster.

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Data on file. Freed MI. Am J Cardiol ; — Bakris G, et al.

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J Hum Hypertens ; — Natali A, et al. Diabetes ; 51 Suppl. Freed M, et al.

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Diabetologia ; 43 Suppl. Haffner S, et al. Circulation ; — Atherosclerosis, cardiovascular disease Festa A, et al. Circulation ; —47; Reaven GM, et al. Annu Rev Med ; — Systolic and diastolic blood pressure were assessed over a hour period at baseline and at week At 52 weeks, both systolic and diastolic blood pressure were significantly reduced in the rosiglitazone group when compared with the sulfonylurea group.

Cardiovascularis kockázatcsökkentés a diabetológus szemével

This was despite both groups achieving similar glycemic control. Ez felvetette a telmisartan alkalmazásának előnyösségét az inzulinrezisztens hipertóniás betegekben. Ugyanakkor az Avandia mellett problémás lehet ennek a kommunikációja, továbbá problémás lehet, hogy a Boehringer — Avandiával nem rendelkezvén - elindulhat ezzel a kommunikációval.

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  • Cardiovascularis kockázatcsökkentés a diabetológus szemével - ppt letölteni

Mindenekelőtt tekintsük át a tényeket szakmai szempontból, majd térjünk vissza a kommunikáció kérdésére. Hypertension ;