Gestational diabetes research questions,
Co-supervisor: Dr. Besides the reorganization of striped muscles, the cardiac muscle is also affected.
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The most common cardiac manifestations are consuction and other heart rhythm disturbances, which are caused by the changes in the heart's pacemaker and conducive systems, due to muscle reorganization. In the course of our research we aim to investigate the role of invasive electrophysiological examination in the cardiologic risk evaluation in myotonic dystrophy.
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Cardiologic risk evaluation in myotonic dystrophy - role of implantable loop recorder Gestational diabetes research questions Dr. Comparison of conventionally performed and zero-fluoroscopic catheter ablation in AV nodal reentry tachycardias Supervisor: KUPÓ, Péter Zero-fluoroscopic ablation techniques reduce the harmful effects of ionizing radiation during electrophysiology procedures.
We aim to test the efficiency and safety of a zero-fluoroscopic strategy using 3D electroanatomic mapping system for diagnostics and radiofrequency ablation of AV nodal reentry tachycardias in a retrospective study. Comparison of conventionally performed and zero-fluoroscopic catheter ablation in paroxysmal supraventricular tachycardias Supervisor: KUPÓ, Péter Zero-fluoroscopic ablation techniques — have been able to use since september of in Pécs - reduce the harmful effects of ionizing radiation during electrophysiology procedures.
We aimed to test the efficiency and safety of a zero-fluoroscopic strategy using 3D electroanatomic mapping system for diagnostics and radiofrequency ablation of supraventricular tachycardias SVT in a retrospective study. Comparison of cryoballoon and ablation-index guided radiofrequency catheterablation in paroxysmal atrial fibrillation Supervisor: KUPÓ, Péter The number of transcatheter ablation procedures for atrial fibrillation grows year by year in Hungary.
During the procedure pulmonary vein isolation is performed. Lately the cryoballoon technique has become widespread available besides radiofrequency ablation. Moreover, contact force sensing catheters has been available in radiofrequency ablation.
In our research the procedures performed by these two different methods will be compared and analyzed.
Comparison of intracardiac echocardiography-guided versus conventionally performed cavotricuspidal isthmus ablation in patients with atrial flutter Supervisor: KUPÓ, Péter Cavotricuspidal isthmus CTI is the target of the ablation for patients with atrial flutters. These procedures are usually performed by only-fluoroscopy navigation. However, use of intracardiac echocardiography for CTI ablation has become widespread in recent years.
In our study we aim to compare conventional, only fluoroscopy-guided vs ICE-guided CTI ablations in patients underwent invasive electrophysiologic procedures due to atrial flutters. Comparison of procedural parameters of patients undergoing pulmonary vein isolation with conventional, steerable sheaths vs.
Conventionally, these procedures are performed with the use of steerable sheaths. Recently, steerable sheaths that can be visualized on 3D mapping system are available which can reduce the use of fluoroscopy during these procedures. In our research the procedures performed by these two different tools will be compared and analyzed.
Comparison of the effectiveness of cryoballoon and radiofrequecy catheterablation in persistent atrial fibrillation Co-supervisor: Dr. Lately the cryoballoon technique has became widespread available besides radiofrequency ablation. In most cases the cause of sudden cardiac death is an occult cardiac disease. A lot of researches have already shown the differences between the phisiological sport heart and pathological cardiac conditions. In this study we examine sportsmen competing in different sport arts.
Special ECG, particular echocardiographic examination furthermore spiroergometry are performing. The sportsmen with pathological results have a heart MRI examination, too.
In the latter situation, full revascularization plays an important role. The different catheter based techniques are discussed, which are utilized during the diagnostic and interventional part in the catheter based revascularization. Due to the multiple associations of the vegetative nervous system, several factors affect HRV.
On one hand it means the wide range of applicability, however, on the other hand, results in low specificity. Accurate measurement requires special study-design, technical conditions and presentation. The topic covers both methodical and clinical investigations including cooperation with other specialties as well.
Identification of novel biomarkers in acute myocardial infarction Supervisor: SZOKODI, István Acute coronary syndrome results mainly from rupture of an inflamed thin-capped plaque with secondary thrombus formation. Chemokines and cytokines have been suggested to orchestrate the inflammatory processes during atherogenesis, plaque destabilization, and infarct healing.
We aim to identify novel biomarkers e. Investigation of 3-dimensional reconstruction of coronary angiography with computational fluid dynamics and its clinical significance Supervisor: BÁLINT, Alexandra Several methods are available for the diagnosis of coronary stenosis, of which the detection of the hemodynamic relevance is limited.
The most significant developmental need and tendency focus on are techniques that determine gestational diabetes research questions fractional flow reserve FFR without the use of an invasive pressure measuring wire by calculating non-invasive virtual fractional flow reserve vFFR from a three-dimensional reconstruction of the coronary angiogram. The three-dimensional 3D geometry gestational diabetes research questions the coronary artery can be analyzed from the coronarography with 3D reconstruction software.
Computational fluid dynamics CFD allows a comprehensive, in silico study of fluid properties after 3D reconstruction of vascular structures. In addition to the existing study data, it can be assumed that CFD examination of the coronary sections results in the detection of flow parameters that are important for plaque progression.
Heart Institute · Student Researchers\' Society Topics · UP MS
Modern echocardiographic techniques and biomarkers in the diagnosis of heart failure Supervisor: FALUDI, Réka In addition to the classical, widespreadly used echocardiographic methods more new, special techniques tissue Doppler imaging, strain, strain a kezelés a cukorbetegség yanuvia have been developed.
Systolic or diastolic functions of both the left and right ventricles as well as the atria are investigated by applying these new techniques in some special diseases systemic sclerosis, COPD, restrictive cardiomyopathy, etc.
In addition to the echocardiographic methods, serum levels of some biomarkers e.
These factors can activate specific signaling pathways, such as mitogen-activated protein kinases MAPKs and calcineurin, which leads to increased expression of certain genes characteristic of cardiac hypertrophy, the so-called fetal gene program.
Transcription factors play crucial role in integrating these cytosolic signaling cascades.
Our studies may pave the way for the development of novel strategies in combating adverse remodeling and heart failure. Our aim is to investigate if there is any sign of myocardial or vascular dysfunction even before the diagnosis of gestational diabetes.
First Affiliated Hospital, Sun Yat-Sen University Rövid összefoglaló The study is to investigate the impact of blood glucose management at the first trimester of pregnant women with gestational diabetes on the maternal and fetal outcomes and metabolic disorder.
Echocardiography is performed to examine the systolic and diastolic function of the heart. An easy-to-perform oscillometric method Arteriograph will be used to measure arterial stiffness parameters.
Non-coding RNAs in pathological cardiac remodeling Supervisor: SZOKODI, István The development of cardiac remodeling is associated with fundamental changes in the molecular programs of the heart including the reactivation of fetal gene programs, deregulation of neurohormonal gestational diabetes research questions as well as the activation of senescence and various forms of cell death.
It has long been considered that these gene programs are primarily under the control of protein-based regulatory systems i. Understanding the functional significance of these non-coding RNA transcripts in versatile cellular processes is the subject of intense investigation. According to the most recent estimates, the human genome encodes for ~ different microRNAs and ~ long non-coding RNAs.
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